This panel is designed to measure the health and recovery of the Hypothalamic-Pituitary-Testicular Axis (HPTA) after attempting to normalize it spontaneously or with the use of Post-Cycle Therapy (PCT) with hCG, clomiphene and/or tamoxifen. PCT is prescribed by some physicians for men who stop testosterone replacement therapy (TRT) or Anabolic-Androgenic Steroids (AAS).
Testosterone replacement therapy and anabolic steroids can lead to HPTA (Hypothalamic-Pituitary-Testicular Axis- shown in figure below) dysfunction. Supplemental testosterone can inhibit the release of the body’s own testosterone production through negative feedback inhibition on LH levels. This feedback inhibition also results in suppression of FSH levels, leading to suppression of sperm production (spermatogenesis).
It is suggested that this panel be done no sooner than 4 weeks after PCT cessation and in a fasting state (morning time)
Tests included:
– Sensitive Estradiol (E2) by Liquid Chromatography/Mass Spectrometry (LC/MS assay used to more accurately measure estradiol in men)
– Total and Free Testosterone [ Free T: direct analog/radioimmunoassay (RIA); Total T:electrochemiluminescence immunoassay (ECLIA) ]
– Luteinizing Hormone (LH) (Responsible for activating Leydig testicular cells to produce your own testosterone). This hormone is shut down by testosterone replacement or AAS.
– Follicle Stimulating Hormone (FSH) (Responsible for activating Sertoli testicular cells to produce sperm). This hormone is shut down by testosterone replacement or AAS.
– CBC – Complete Blood Count (Includes hematocrit)
– CMP – Comprehensive Metabolic Panel (Includes liver and kidney function, glucose and electrolytes)
BUY POST PCT PANEL
Recent Posts
Does Testosterone Increase the Chance for a Heart Attack?
"Many healthcare providers hesitate to initiate men on testosterone replacement therapy (TRT) due to the belief that these treatments increase the risk of cardiovascular...
Nelson Vergel’s Top 10 Testosterone Replacement Commandments (Video)
Nelson Vergel's Top 10 Testosterone Replacement Commandments (Video)
Nelson Vergel, author of Testosterone: A Man's Guide (Amazon.com) and founder of ExcelMale.com and DiscountedLabs.com, talks about...
Effect of DHT on Prostate and Sexual Function: Review of Studies
Benefits associated with lowered serum DHT levels after 5α-reductase inhibitor (5AR-I) therapy in men have contributed to a misconception that circulating DHT levels are...
Two Blood Test Companies in the United Kingdom (UK)
I do not much about them but I am asked frequently about blood testing labs in the UK since my company, DiscountedLabs.com, only services...
Interview with Lee Myer, Author of “Natural vs Testosterone Therapy”
This is an interview with my good friend Lee Myer, founder of PeakTestosterone.com and author of "Natural vs Testosterone Therapy". Lee has been a...